To run a Nanogan, the Faction of the Nanogan you wish to run must match the Faction of at least one of the three Bakugan on your team. The Nanogan serves as an accessory to your team, it does not replace any of the Bakugan on your team. The physical Nanogan toy is not required to play a Nanogan.
Nanogan Cards are specialized cards that come with Nanogan. They do not get shuffled into the main deck, and instead stay beside the deck as up to three separate cards. When a Nanogan is used, it is flipped over, and provides the Bakugan it is used one of the two bonuses present on its card, which the cores attached to the entire team contribute to activating. After the turn, the Nanogan card is rendered unusable. Unlike Geogan, it is possible to use multiple Nanogan in one turn.
List of Nanogan